Medical Device · Glaucoma

Glaucoma is a two-pressure disease.

QMAX is the first implant built to treat it that way.

Translaminar gradientTranslaminar pressure gradientThe pressure difference across the optic nerve head between IOP and CSF pressure. A sustained gradient strains nerve fibers.

IOPIntraocular pressureFluid pressure inside the eye. Most glaucoma therapies aim to lower IOP.Translaminar pressure zoneTranslaminar pressure zoneThe region across the optic nerve head where the pressure difference between IOP and CSF pressure builds and strains nerve fibers — not a single point, but where the opposing pressures meet.ICPCerebrospinal fluid pressurePressure in the fluid space around the optic nerve, behind the lamina cribrosa.

QMAX

First-in-class glaucoma implant

A permanently implanted, bleb-free, micro-shunt that relieves strain on the optic nerve by equalizing the pressure difference over the optic nerve headOptic nerve headWhere retinal nerve fibers exit the eye. QMAX is designed to relieve strain at this point., addressing the underlying mechanism behind vision loss in glaucoma.

Cross-section of QMAX implant equalizing pressure at the optic nerve head.
IOPIntraocular pressureFluid pressure inside the eye. Most glaucoma therapies aim to lower IOP.Optic nerve headOptic nerve headWhere retinal nerve fibers exit the eye. QMAX is designed to relieve strain at this point.ICPCerebrospinal fluid pressurePressure in the fluid space around the optic nerve, behind the lamina cribrosa.
QSCOPE endoscopic delivery system close-up.

Endoscopic delivery.

QSCOPE, a single-use endoscopic system designed for the high turnover workflow.

Clinical illustration of a filtering bleb after glaucoma surgery.

No bleb.

A closed pathway, with no bleb to manage or revise.

Diagram of QMAX relieving pressure across the optic nerve.

No anti-fibrotics.

No reliance on mitomycin C or anti-scarring agents.

Glaucoma is the world's leading cause of irreversible blindness

Worldwide, over 80 million people live with glaucoma. Today's surgeries and drugs aim to lower eye pressure, and yet vision loss continues.

We have been solving only half the problem

Healthy Visual Field

80M+

people living with glaucoma globally

1 in 4

patients will go blind in at least one eye from glaucoma

The optic nerve is exposed to two different pressures.

Inside the eye

The pressure inside the eye.

Cross-section of the eye showing pressure from within the globe.

Around the optic nerve

The pressure in the fluid space around the optic nerve.

Optic nerve head showing opposing pressure from inside the eye and around the nerve.

The pressure difference between the inside of the eye and the fluid space around the optic nerve is called the translaminar gradientTranslaminar pressure gradientThe pressure difference across the optic nerve head between IOP and CSF pressure. A sustained gradient strains nerve fibers.. This pressure strains the nerve and kills vision.

Treating IOPIntraocular pressureFluid pressure inside the eye. Most glaucoma therapies aim to lower IOP. alone leaves half the equation untouched.

Cause

Glaucoma damages vision when sustained pressure strains the optic nerve headOptic nerve headWhere retinal nerve fibers exit the eye. QMAX is designed to relieve strain at this point.. Fluid inside the eye (intraocular pressure) and fluid around the optic nerve both matter. When the translaminar gradientTranslaminar pressure gradientThe pressure difference across the optic nerve head between IOP and CSF pressure. A sustained gradient strains nerve fibers. between them stays elevated, nerve fibers are damaged and sight is lost — even when eye pressure looks acceptable on its own.

Symptoms

Glaucoma is often called the silent thief of sight because it can progress with few or no early symptoms. Peripheral vision may narrow first; over time, untreated disease can lead to tunnel vision and irreversible blindness. Regular eye exams are essential because damage can occur before a person notices vision loss.

Current treatments

Most care today lowers IOPIntraocular pressureFluid pressure inside the eye. Most glaucoma therapies aim to lower IOP. with eye drops, laser therapy, or surgery such as trabeculectomy, tube shunts, and MIGS devices. These approaches can slow progression, but they focus on pressure inside the eye — not the full pressure difference across the optic nerve headOptic nerve headWhere retinal nerve fibers exit the eye. QMAX is designed to relieve strain at this point. that drives nerve strain.

Complications

Filtering surgeries can require bleb management, anti-fibrotic agents, and revision procedures. Infection, scarring, hypotony, and long-term bleb failure remain risks. Vision loss can continue despite apparently controlled IOPIntraocular pressureFluid pressure inside the eye. Most glaucoma therapies aim to lower IOP., particularly in normal-tension glaucoma.

Built by surgeons, engineers, and operators.

LIQID is led by a glaucoma surgeon-founder and a multidisciplinary team across biomedical engineering, clinical research, regulatory, and quality, headquartered in Minneapolis.

LIQID Medical was founded to do one thing well: address glaucoma at the mechanism. The company is headquartered in Minneapolis and led by people who have spent careers inside this disease.

Headquarters: Minneapolis, Minnesota, United States (est. 2017).

Supported by

Investors and innovation partners backing the path from mechanism to clinic — capital and grant support for QMAX through Bridge and toward Series A.

CDI CapitalSAB FoundationTIASavant

Three ways you can move QMAX forward.

Investors

We are advancing QMAX through Bridge financing toward Series A and US clinical milestones. If preventing blindness from glaucoma fits your thesis, we want to talk.

Open an investor conversation

Strategic partners

Surgical innovators, distributors, and strategics: QMAX is built for the high turnover workflow and the next paradigm of glaucoma care.

Discuss partnership

Talent

Email info@liqidmedical.com

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